She married Jaime de Marichalar y Sáenz de Tejada, son of the Count and Countess of Ripalda, on 18 March 1995, in Seville Cathedral, Seville, at which time her father conferred on her the title Duchess of Lugo for life.has two children:
His Excellency Felipe Juan Froilán de Todos los Santos de Marichalar y de Borbón, Grandee of Spain (Grande de España) (born 17 July 1998)
Her Excellency Victoria Federica de Todos los Santos de Marichalar y de Borbón, Grandee of Spain (Grande de España) (born 9 September 2000)